Piotr Ponikowski Selected Research

Purinergic P1 Receptor Antagonists

11/2019	Hyperkalemia and Treatment With RAAS Inhibitors During Acute Heart Failure Hospitalizations and Their Association With Mortality.
1/2018	Prognostic Significance of Creatinine Increases During an Acute Heart Failure Admission in Patients With and Without Residual Congestion: A Post Hoc Analysis of the PROTECT Data.
1/2017	Associations of Body Mass Index With Laboratory and Biomarkers in Patients With Acute Heart Failure.
1/2016	Combining Diuretic Response and Hemoconcentration to Predict Rehospitalization After Admission for Acute Heart Failure.
5/2015	Worsening Heart Failure Following Admission for Acute Heart Failure: A Pooled Analysis of the PROTECT and RELAX-AHF Studies.
1/2014	Renal function trajectories and clinical outcomes in acute heart failure.
1/2014	Predictors of postdischarge outcomes from information acquired shortly after admission for acute heart failure: a report from the Placebo-Controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized With Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function (PROTECT) Study.
11/2011	Impact of serial troponin release on outcomes in patients with acute heart failure: analysis from the PROTECT pilot study.
5/2011	Effects of the adenosine A1 receptor antagonist rolofylline on renal function in patients with acute heart failure and renal dysfunction: results from PROTECT (Placebo-Controlled Randomized Study of the Selective Adenosine A1 Receptor Antagonist Rolofylline for Patients Hospitalized with Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function).
1/2010	Design and rationale of the PROTECT study: a placebo-controlled randomized study of the selective A1 adenosine receptor antagonist rolofylline for patients hospitalized with acute decompensated heart failure and volume overload to assess treatment effect on congestion and renal function.

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Piotr Ponikowski Research Topics

Disease

363	Heart Failure 08/2022 - 04/2003
45	Iron Deficiencies 01/2022 - 01/2008
22	Cardiomyopathies (Cardiomyopathy) 01/2022 - 02/2007
21	Atrial Fibrillation 01/2022 - 01/2012
19	Dyspnea (Shortness of Breath) 01/2022 - 01/2010
17	Type 2 Diabetes Mellitus (MODY) 08/2022 - 02/2015
17	Renal Insufficiency (Renal Failure) 01/2020 - 04/2009
13	Myocardial Infarction 01/2022 - 01/2008
13	Stroke (Strokes) 12/2019 - 03/2012
12	Inflammation (Inflammations) 01/2022 - 06/2006
12	Systolic Heart Failure 01/2021 - 01/2009
11	Hypoxia (Hypoxemia) 01/2022 - 06/2013
10	Anemia 11/2021 - 02/2007
9	Chronic Renal Insufficiency 01/2022 - 05/2011
9	Hypotension (Low Blood Pressure) 01/2022 - 01/2017
9	Heart Diseases (Heart Disease) 03/2021 - 01/2011
8	Coronary Artery Disease (Coronary Atherosclerosis) 01/2022 - 01/2003
8	Cardiovascular Diseases (Cardiovascular Disease) 11/2020 - 01/2011
8	Ischemic Stroke 10/2016 - 05/2012
7	Disease Progression 12/2021 - 10/2010
7	Hypertension (High Blood Pressure) 12/2019 - 08/2012
5	Tachycardia (Tachyarrhythmias) 01/2022 - 10/2013
5	Acute Coronary Syndrome 09/2021 - 01/2011
5	Central Sleep Apnea (Central Sleep Apnea Syndrome) 01/2021 - 01/2013
5	Weight Loss (Weight Reduction) 02/2016 - 05/2013
5	Hemorrhage 09/2015 - 05/2012
4	Neoplasms (Cancer) 01/2022 - 01/2011
4	Body Weight (Weight, Body) 01/2019 - 02/2007
4	Diabetes Mellitus 10/2017 - 09/2010
4	Obesity 01/2017 - 02/2007

Drug/Important Bio-Agent (IBA)

44	IronIBA 05/2022 - 01/2008
40	Biomarkers (Surrogate Marker)IBA 05/2022 - 09/2007
34	dapagliflozinIBA 08/2022 - 01/2019
27	Brain Natriuretic Peptide (Natrecor)FDA Link 12/2021 - 11/2007
23	SodiumIBA 01/2022 - 03/2010
20	Natriuretic PeptidesIBA 01/2022 - 03/2006
20	ferric carboxymaltoseIBA 01/2022 - 11/2009
20	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 09/2005
18	vericiguatIBA 01/2022 - 09/2014
18	rolofyllineIBA 11/2019 - 01/2010
17	DiureticsIBA 01/2022 - 01/2010
17	empagliflozinIBA 01/2022 - 11/2017
15	Ferritins (Ferritin)IBA 05/2022 - 12/2009
15	Warfarin (Coumadin)FDA LinkGeneric 04/2019 - 05/2012
14	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 04/2019 - 05/2012
13	Transferrin (beta 2 Transferrin)IBA 05/2022 - 12/2009
13	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2022 - 11/2017
13	CreatinineIBA 12/2019 - 03/2010
12	pro-brain natriuretic peptide (1-76)IBA 12/2021 - 09/2007
11	RelaxinIBA 12/2021 - 04/2009
10	Sodium-Glucose Transport ProteinsIBA 01/2022 - 11/2019
10	SymportersIBA 01/2022 - 11/2017
10	Testosterone (Sustanon)FDA Link 01/2021 - 01/2003
10	Purinergic P1 Receptor AntagonistsIBA 11/2019 - 01/2010
9	Hemoglobins (Hemoglobin)IBA 11/2021 - 02/2007
9	Soluble Guanylyl CyclaseIBA 10/2020 - 03/2013
9	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 08/2020 - 06/2004
8	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2007
8	NitrogenIBA 01/2022 - 01/2014
8	Mineralocorticoid Receptor AntagonistsIBA 01/2021 - 06/2012
7	Interleukin-6 (Interleukin 6)IBA 05/2022 - 03/2013
7	Oxygen (Dioxygen)IBA 01/2022 - 02/2007
7	Hormones (Hormone)IBA 06/2021 - 12/2009
7	Pharmaceutical PreparationsIBA 01/2021 - 01/2010
7	Urea (Carbamide)FDA LinkGeneric 01/2017 - 01/2014
7	Adenosine (Adenocard)FDA LinkGeneric 01/2017 - 04/2003
7	AndrogensIBA 12/2016 - 01/2009
6	Uric Acid (Urate)IBA 01/2022 - 04/2003
6	Atrial Natriuretic Factor (ANF)IBA 09/2016 - 11/2007
5	HepcidinsIBA 05/2022 - 01/2013
5	Transferrin Receptors (Transferrin Receptor)IBA 05/2022 - 05/2018
5	omecamtiv mecarbilIBA 01/2022 - 03/2016
5	Cardiac MyosinsIBA 01/2022 - 03/2016
5	Insulin (Novolin)FDA Link 01/2022 - 09/2005
5	AlbuminsIBA 06/2021 - 01/2014
5	AdrenomedullinIBA 01/2020 - 05/2010
5	PotassiumIBA 11/2019 - 06/2012
5	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 11/2019 - 06/2004
5	TroponinIBA 01/2019 - 08/2011
5	AnticoagulantsIBA 01/2019 - 01/2012
5	Adenosine A1 ReceptorIBA 01/2017 - 05/2011
5	Darbepoetin alfa (Aranesp)FDA Link 03/2012 - 02/2007
4	sacubitril and valsartan sodium hydrate drug combinationIBA 01/2022 - 01/2017
4	Growth Differentiation Factor 15IBA 01/2022 - 09/2007
4	ReninIBA 12/2021 - 12/2019
4	Angiotensin Receptor AntagonistsIBA 01/2020 - 01/2017
4	Lactic Acid (Lactate)FDA LinkGeneric 01/2019 - 01/2018
4	IvabradineIBA 11/2017 - 03/2009
4	finerenoneIBA 07/2016 - 06/2012
4	Prostaglandins AIBA 05/2016 - 11/2013
4	Troponin T (Troponin T1)IBA 01/2016 - 11/2011

Therapy/Procedure

108	Therapeutics 08/2022 - 06/2004
22	Patient Readmission 11/2021 - 02/2012
15	Length of Stay 12/2020 - 01/2010
12	Drug Therapy (Chemotherapy) 01/2022 - 01/2008
5	Electric Countershock (Cardioversion) 01/2015 - 10/2012
4	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 01/2022 - 08/2015
4	Heart Transplantation (Grafting, Heart) 11/2021 - 08/2012
4	Intravenous Infusions 01/2019 - 01/2013
4	Critical Care (Surgical Intensive Care) 01/2019 - 10/2008